Pathophysiological classification of chronic rhinosinusitis

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Pathophysiological classification of chronic rhinosinusitis

BACKGROUND Recent consensus statements demonstrate the breadth of the chronic rhinosinusitis (CRS) differential diagnosis. However, the classification and mechanisms of different CRS phenotypes remains problematic. METHOD Statistical patterns of subjective and objective findings were assessed by retrospective chart review. RESULTS CRS patients were readily divided into those with (50/99) an...

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Histopathological classification of refractory chronic rhinosinusitis with nasal polyps.

OBJECTIVE To delineate the histopathological characteristics of nasal mucosa in refractory chronic rhinosinusitis with nasal polyps (CRSwNP) in order to demonstrate subtypes of nasal polyps and their potential relation with lower airway comorbidity. STUDY DESIGN Clinical- and pathological-based cross-sectional study Methods: Nasal polyp specimens were prospectively collected from patients wit...

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Epidemiology of chronic rhinosinusitis.

PROBLEM OF DEFINITION The discrepancy of definitions results mainly from the use of diVerent criteria such as symptom duration or intensity, the type of selected symptoms, and also from the need for and lack of other exploration methods such as imaging or bacteriological culture. In the definition proposed by the International Conference on Sinus Disease in 1993 the criteria for chronic sinusit...

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Evaluation of Children with Chronic Rhinosinusitis after Adenotonsillectomy

Introduction: Chronic rhinosinusitis (CRS), defined as an inflammatory process involving the paranasal sinuses that continues for at least three months, is a major cause of morbidity in the pediatric population and a difficult entity to treat with a poorly defined pathophysiology. The cornerstone of treatment for children with CRS remains aggressive antibiotic therapy, but many patients fail t...

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Chronic rhinosinusitis in children.

Chronic rhinosinusitis (CRS) affects nearly 37 million people in the United States each year and accounts for approximately $6 billion in direct and indirect health care costs. Despite its prevalence and significant impact, little is known about its exact cause and pathophysiology, and significant controversy remains regarding appropriate treatment options. Basic science research, however, has ...

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ژورنال

عنوان ژورنال: Respiratory Research

سال: 2005

ISSN: 1465-993X

DOI: 10.1186/1465-9921-6-149